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Vaccine Savings Made Simple for 340B Covered Entities

By Apexus | December 1, 2025

For 340B covered entities, purchasing and administering vaccines is crucial for preventing disease in your communities, particularly among vulnerable patient populations. Because vaccines are not considered covered outpatient drugs in the 340B Drug Pricing Program, they do not have a 340B price. This means that covered entities could have significant expense on vaccines without any relief in costs. To address this, the 340B Prime Vendor Program (PVP), managed by Apexus, has partnered with vaccine manufacturers to provide discounts on these valuable products—including seasonal vaccines—to all 340B covered entities, regardless of size.

The PVP Vaccine Portfolio

The PVP vaccine portfolio includes a range of vaccines with discounted prices available to all 340B covered entities. Contracted vaccine products are available through a variety of avenues: enrollment-based, committed purchasing, or tiered-pricing programs. Entities also have several options for ordering products: directly from the manufacturer’s website, through their distributor, or both. The PVP vaccine portfolio provides:

Flu Vaccine Reservations

The PVP Flu Vaccine Program is a critical component of the PVP vaccine portfolio. By pre-booking flu vaccines between January and March, covered entities can secure additional discounts on seasonal flu vaccines.

Why purchase influenza vaccines through the PVP?

Accessing Information and Resources

PVP participants can access discounted vaccine products and review available programs on the PVP secure website. The site lists all manufacturers and products on contract, along with committed and enrollment-based programs. For assistance with accessing the PVP vaccine portfolio, contact Apexus Answers.

By leveraging the PVP Vaccine Portfolio and Flu Vaccine Program, 340B covered entities can reduce costs, streamline vaccine management, and continue to provide essential preventive care to their patients.