340B OPAIS Technical Assistance
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The 340B registration and pricing databases are collectively known as the 340B Office of Pharmacy Affairs Information System (340B OPAIS). Authorized users of 340B OPAIS must have a user account with appropriate roles and permissions granted by HRSA. Visit the HRSA OPA website for additional information.
In accordance with Section 340B(d)(1)(B) of the Public Health Service Act, HRSA is required to collect information from manufacturers to verify the accuracy of the 340B Drug Pricing Program ceiling prices and then make ceiling prices available to covered entities. HRSA has developed an integrated information system, the HRSA 340B Office of Pharmacy Affairs Information System (340B OPAIS), which focuses on three key priorities: security, user accessibility, and data accuracy. For additional information, visit the HRSA OPA website.