Online Learning (OnDemand)

340B Program online learning modules are authored by subject matter experts to align with HRSA policy.

Learn essential compliance elements of the 340B Program by completing the curriculum at your own pace from your home or office.

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340B University online learning modules are designed to provide 340B training to stakeholders on their own schedules. Enrollees have the option to complete all modules to gain new knowledge or focus on specific topics based on their areas of interest. Users who complete all modules and the course evaluation will receive a statement of completion.

Modules are authored by 340B subject matter experts to align with HRSA policy. Completion of the entire curriculum takes approximately 4 hours. Individual modules generally take 10 to 15 minutes to complete and can be taken at the learner’s convenience. Learners may re-enroll in any previously completed modules to update their transcript completion date to the current date for that module. Re-enrolling is commonly used to fulfill employer annual 340B training requirements.

Complete 340B University online modules before attending a 340B University in-person training or virtual offering, such as a workshop or office hours session.

Test drive 340B University Online Learning (OnDemand)

View Module 1: Introduction to the 340B Drug Pricing Program (13 min).

Tailored curricula are available for federally qualified health centers (FQHCs), manufacturers, and distributors.


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Full Curriculum

Module Title


Provides a foundational overview of the 340B Program and serves as a primer for the rest of the modules in the curriculum.

Describes the major stakeholders and their roles in the 340B Program.

Eligibility Overview
24 minutes
Updated June 2021

Outlines the types of 340B-eligible organizations and compliance best practices for covered entities.

340B Pricing
15 minutes

Describes how the 340B prices are calculated and the functions of manufacturers, wholesalers, and HRSA in 340B pricing.

Compliance Cornerstones
14 minutes
Updated Nov 2020

Provides an overview of the compliance cornerstones of the 340B Program, including prevention of diversion and duplicate discounts, GPO Prohibition, and the Orphan Drug Exclusion.

340B and Medicaid
12 minutes
Updated Oct 2020

Defines duplicate discounts and how they occur, as well as stakeholder roles in identifying and/or preventing them.

HRSA’s Medicaid Exclusion File
9 minutes
Updated Oct 2020

Discusses the role of the Medicaid Exclusion File (MEF) in preventing duplicate discounts and the uses of the MEF by 340B stakeholders.

Provides an overview of the various drug delivery models in 340B implementation and identifies decision points and best practices for each model.

GPO Prohibition
10 Minutes

Defines the GPO Prohibition, which entities are subject to its requirements, and when an entity may use a GPO in a compliant manner.

Defines the Orphan Drug Exclusion, which entities are subject to its requirements, and approaches for compliance.

Contract Pharmacy
16 Minutes

Discusses compliance and operational considerations for using a contract pharmacy arrangement.

Discusses compliance and operational considerations of using an entity-owned pharmacy model.

Mixed-Use Areas
11 Minutes

Discusses 340B inventory models in mixed-use areas of a hospital and the role in compliance of split-billing software and multiple purchasing account types.

Discusses the process of HRSA and manufacturer audits of covered entities, as well as types of self-audits to maintain a compliant 340B program.

PVP Contracting
12 Minutes

Describes the role and benefits of the Prime Vendor Program (PVP), including contracting solutions to provide value for PVP participants.

Tailored to executive leadership; discusses the value and risks to an organization by participating in the 340B Program.

Outlines compliance and operational requirements for manufacturers, including the requirements of the pharmaceutical pricing agreement.

Outlines compliance and operational best practices for distributors, including the role in processing chargebacks.

Live Education Event Calendar

Find out more about 340B University, which provides basic information about 340B through in-person live events.