Apexus Answers

Apexus Answers

Your source for reliable 340B information that is aligned with HRSA policy. Recognized by 2024 Stevie Awards for customer satisfaction.

Have questions or need help?

If you have questions about the 340B Drug Pricing Program or the Prime Vendor Program (PVP), contact Apexus Answers. This free information resource is available by phone, email, or online chat and offered to PVP participants and all stakeholders.

Apexus Answers, celebrating ten years of service and support, aligns with HRSA policy and guidance. Our staff is in constant communication with HRSA to ensure that information is accurate and up to date. If our staff members don’t have the answer to your question, they will anonymously forward it to HRSA for clarification.

Important Information

Apexus Answers is live Monday through Friday, from 8:00 am to 5:00 pm Central Time.


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Call: 888.340.2787 >

Frequently Asked Questions

Before contacting Apexus Answers, you can check to see if your question has already been addressed and included in the Frequently Asked Questions (FAQ).

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Topic Examples for Apexus Answers


  • User accounts
  • Registration process
  • Change requests

Guidance on All
340B Policy

  • The patient definition
  • GPO Prohibition
  • Purchasing/inventory

Eligibility Questions

  • Covered entities
  • Outpatient facilities
  • Contract pharmacies

Outpatient Drugs

  • Definition of covered outpatient drugs
  • Exclusions, orphan drugs, and GPO Prohibition
  • Tools/resources

Duplicate Discounts

  • State agency contact information
  • Medicaid Exclusion File
  • General policy


  • Assistance with login
  • Recertify/decertify
  • Status of submission/OPA review


  • 340B OPAIS pricing system
  • 340B PVP catalog
  • Value-added products


  • 340B pricing submission
  • Pharmaceutical pricing agreement
  • 340B PVP participants


  • Covered entity eligibility
  • Shipping addresses
  • 340B PVP participants
Please be advised that information from Apexus, LLC is not dispositive with respect to compliance with or participatory status in the 340B Drug Pricing Program. 340B entities are ultimately responsible for 340B Program compliance, and Apexus encourages entities to include legal counsel as part of their program integrity efforts.

The responsibility to ensure compliance with 340B Program requirements remains with covered entities and manufacturers that participate. Information received from vendors, consultants, and other third parties cannot be assumed to be compliant with HRSA policy.

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