340B Prime Vendor Program

HRSA allows eligible entities to immediately enroll for the 340B Program during the Public Health Emergency Declaration by the Secretary, rather than waiting for the normal quarterly registration period. HRSA believes this will enable these entities to meet the needs of the residents affected by this disaster. If you are in a territory listed below and would like to enroll, please contact the 340B Prime Vendor Program at apexusanswers@340Bpvp.com or 1.888.340.BPVP (2787).

Become a 340B Participant

The registration component of the 340B Office of Pharmacy Affairs Information System (340B OPAIS) is now available at (https://340bopais.hrsa.gov).

Information regarding flexibilities allowed during a Public Health Emergency Declaration by the Secretary is available at (https://www.hrsa.gov/opa/eligibility-and-registration/index.html)

New registrations are accepted October 1-15,
January 1-15, April 1-15 and July 1-15.


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