About Apexus | 340B Prime Vendor Program

340B Prime Vendor Program



The 340B Prime Vendor Program Managed by Apexus®, is a contract awarded by the Health Resources and Services Administration (HRSA), which is responsible for administering the 340B Drug Pricing Program. As the Prime Vendor, Apexus contracts with manufacturers and distributors to help ensure access to discounted medications, provides 340B education to all stakeholders, and helps support program integrity through technical assistance.

The 340B Prime Vendor Program is a voluntary program for covered entities and manufacturers alike. There is no fee for eligible covered entities to enroll and participate in the Prime Vendor Program.





Since 2004, the Prime Vendor Program (PVP) has brought together nearly 100 manufacturers and 40,000 covered entity sites to achieve lower 340B drug pricing for those who need it most. Contracting with PVP is voluntary for manufacturers and provides value for both stakeholders.


The PVP partners with 29 national, regional, and specialty distributors to manage distribution networks. These distribution options provide choice in the marketplace, which drives value. Serving as a central source to oversee these distributors, the PVP supports 340B compliance by ensuring pricing integrity in these distributor relationships.


340B PVP collaborates with all types of 340B stakeholders to deliver free, nationwide, online, and in-person education through the 340B University and 340B University OnDemand. Our PVP website features additional educational resources, including HRSA answers to frequently asked questions and compliance tools and templates. All at no cost.


All 340B stakeholders have equal access to technical assistance by contacting the Apexus Answers call center. We provide HRSA-aligned answers to over 2,000 questions a month, ranging from basic to complex, via phone 888.340.BPVP (2787), live chat, and email. We are here to help you navigate through the 340B Program.


We align manufacturers, distributors, and covered entities to facilitate resolving manufacturer overcharges to covered entities. By working through existing relationships and technology, the PVP delivers an effective and efficient way to collaborate: the  340B PVP Manufacturer Refund Service. Since 2010, our team has returned nearly $120 million in refunds to covered entities.



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